The immune system acts as our body’s own homeland security department, working nonstop to identify harmful invaders and prevent them from wreaking havoc on us. It is extremely complex, compared to such other vital systems as the circulatory and pulmonary systems. The...
Group A Streptococcus (GAS) is a bacteria that manifests itself in a variety of diseases, from strep throat to neuroautoimmune psychiatric disorders, such as pediatric acute-onset neuropsychiatric syndrome (PANS) or pediatric autoimmune neuropsychiatric disorder...
Current case definitions of schizophrenia (DSM-5, ICD), made through a consensus among experts, are not cross-validated and lack construct reliability validity. The aim of this paper is to explain how to use bottom-up pattern recognition approaches to construct a...
In some instances, when chemicals bind to proteins, they have the potential to induce a conformational change in the macromolecule that may misfold in such a way that makes it similar to the various target sites or act as a neoantigen without conformational change....
Recently, a breakdown of paracellular and vascular pathways and activated neuroimmune and oxidative pathways were established in (deficit) schizophrenia. The aim of the current study was to delineate a) the differences in these pathways between stable phase, first...
