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Detection of Mycoplasma genus and Mycoplasma fermentans by PCR in patients with Chronic Fatigue Syndrome
Multiplex PCR for the detection of Mycoplasma fermentans, M-hominis and M-penetrans in cell cultures and blood samples of patients with chronic fatigue syndrome
A multiplex polymerase chain reaction (PCR) was initially developed to detect the presence of mycoplasma genus DNA sequences in cell cultures and to differentiate between three human pathogenic mycoplasma species simultaneously. The assay in turn, proved to be a...
The Relationship Between Chronic Fatigue Syndrome and Chemical Exposure
Overlapping symptomatologies between chronic fatigue syndrome (CFS) and chemical sensitivity have been observed by different investigators. Interferon-induced proteins 2-5A synthetase and protein kinase RNA (PKR) have been implicated in the viral induction of CFS. The...
Downregulation of RNase L inhibitor correlates with upregulation of interferon-induced proteins (2–5A synthetase and RNase L) in patients with chronic fatigue immune dysfunction syndrome
Chronic Fatigue Immune Dysfunction Syndrome (CFIDS) is a disorder characterized by debilitating fatigue associated with immunological abnormalities and cognitive impairments. The recently cloned RNase L Inhibitor (RLI) gene encodes a specific protein which is believed...
Elevated apoptotic cell population in patients with chronic fatigue syndrome: the pivotal role of protein Kinase RNA
A prominent feature of chronic fatigue syndrome (CFS) is a disordered immune system. Recent evidence indicates that induction of apoptosis might be mediated in a dysregulated immune system by the upregulation of growth inhibitory cytokines. Therefore, the purpose of...
Elevated apoptotic cell population in patients with chronic fatigue syndrome: the pivotal role of protein Kinase RNA
A prominent feature of chronic fatigue syndrome (CFS) is a disordered immune system. Recent evidence indicates that induction of apoptosis might be mediated in a dysregulated immune system by the upregulation of growth inhibitory cytokines. Therefore, the purpose of...
Putting chemical and environmental sensitivities in perspective
Chemical sensitivity has been recognized for an extended period. Over the last 30 years or more, there has been a growing number of chemicals to which humans are being exposed. Some people have become sensitive to one or more of these chemicals and present this...
Methyl tertiary-butyl ether antibodies among gasoline service station attendants
Occupational exposure to petroleum products (gasoline) and elevated blood levels of MTBE have been demonstrated among gasoline station attendants. While MTBE and its metabolites have been considered environmentally inert, immunologically these materials could be...
The Effects of Carcinogenic Methylcholanthrene on Carbohydrate Residues of Nk Cells
Occupational exposure to petroleum products (gasoline) and elevated blood levels of MTBE have been demonstrated among gasoline station attendants. While MTBE and its metabolites have been considered environmentally inert, immunologically these materials could be...
Abnormal apoptosis and cell cycle progression in humans exposed to methyl tertiary-butyl ether and benzene containing water
1 In this study we hypothesized that in individuals with certain genetic makeup, MTBE, benzene or their metabolites act as adducts and may induce pro grammed cell death. 2 Our study involved a group of 60 male and female subjects who were exposed to MTBE and benzene-...