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Suppressed Natural Killer Cell Activity in Patients with Silicone Breast Implants: Reversal upon Explantation
We have previously shown that natural killer (NK) cell activity is significantly suppressed in patients with silicone breast implants. These patients were symptomatic and the suppression of natural killer cell activity was associated with additional significant...
Saliva Secretory IgA Antibodies Against Molds and Mycotoxins in Patients Exposed to Toxigenic Fungi
Upper respiratory exposure to different environmental antigens results first in the activation of mucosal immunity and production of IgA antibodies in different secretions including saliva. Despite this there is no study, which addresses secretory antibodies against...
Antibodies to myelin basic protein, myelin oligodendrocytes peptides, α--crystallin, lymphocyte activation and cytokine production in patients with multiple sclerosis
To measure neurone-specific humoral and cellular immune parameters in MRI-positive patients with multiple sclerosis (MS). It has been postulated from animal models for MS and in situ evidence in MS patients that antibodies, activated T cells and proinflammatory...
Biochemical Changes in the Serum of Patients with Chronic Toxigenic Mold Exposures: A Risk Factor for Multiple Renal Dysfunctions
This paper analyzes and presents the biochemical abnormalities in the sera of patients presenting with chronic mycosis in order to investigate the relationship with the risks of multiple renal disorders. The study population (n = 10) consisted of six females and four...
Saliva Secretory IgA Antibodies Against Molds and Mycotoxins in Patients Exposed to Toxigenic Fungi
Upper respiratory exposure to different environmental antigens results first in the activation of mucosal immunity and production of IgA antibodies in different secretions including saliva. Despite this there is no study, which addresses secretory antibodies against...
Mold and Mycotoxins: Effects on the Neurological and Immune Systems in Humans
There can be a complexity of health problems associated with multiple mold exposure. This chapter describes the most recent neuroimmune mechanisms of diseases caused by molds and mycotoxins in humans. The exact biological and chemical actions through which these...
Identification of Diseases that may be Targets for Complementary and Alternative Medicine (CAM)
Complementary and alternative medicine has an enormous challenge to determine how environmental factors such as infection and xenobiotics interact. Effective strategies for early detection, diagnosis, prevention and therapy should then emerge. Despite significant...
Heat Shock Protein and Gliadin Peptide Promote Development of Peptidase Antibodies in Children with Autism and Patients with Autoimmune Disease
Searching for a mechanism underlying autoimmunity in autism, we postulated that gliadin peptides, heat shock protein 60 (HSP-60), and streptokinase (SK) bind to different peptidases resulting in autoantibody production against these components. We assessed this...
Cellular and Humoral Immune Abnormalities in Gulf War Veterans
We examined 100 symptomatic Gulf War veterans (patients) and 100 controls for immunologic assays. The veterans and controls were compared for the percentage of T cells (CD3); B cells (CD19); helper:suppressor (CD4:CD8) ratio; natural killer (NK) cell activity;...
Cross-Reactivity of Aspergillus, Penicillium, and Stachybotrys Antigens Using Affinity-Purified Antibodies and Immunoassay
In this study, the author examined the cross-reactivities of Stachybotrys chartarum, Aspergillus niger/fumigatus, and Penicillium notatum with affinity-purified rabbit sera. The molds were grown for expression of maximum numbers of antigens, after which they were...