Similar to many complex autoimmune diseases, genetic and environmental factors including diet, infection and xenobiotics play a critical role in the development of autism. In this study, we postulated that infectious agent antigens such as streptokinase, dietary...
We measured autoantibodies against nine different neuron-specific antigens and three cross-reactive peptides in the sera of autistic subjects and healthy controls by means of enzyme-linked immunosorbent assay (ELISA) testing. The antigens were myelin basic protein...
Searching for a mechanism underlying autoimmunity in autism, we postulated that gliadin peptides, heat shock protein 60 (HSP-60), and streptokinase (SK) bind to different peptidases resulting in autoantibody production against these components. We assessed this...
During the last several years, there has been growing clinical and scientific evidence that most children with autism suffer from mercury/metal toxicity. Furthermore, there have been many reports from physicians and parents that removal of mercury and other toxic...
One of the advantages of working for 25 years in a research and clinical laboratory is having the opportunity to observe the evolution of a test assay from a crude and nonspecific to a pure and specific level. Between 1975 and 1980, we started our testing in relation...
Studies show that patients with celiac disease react not only with gluten wheat proteins but also with non-gluten wheat components. Our goal was to measure IgG or IgA antibodies against wheat proteins or peptides that would provide the most sensitive method for the...