Based upon the clinical presentation of chronic fatigue syndrome (CFS), we hypothesized that proinflammatory cytokines may play a role in the pathogenesis of the disease. We therefore undertook a retrospective cross-sectional study to examine the role of TNF- in patients with CFS. Our results suggest a significant increase serum TNF- in patients with CFS (P < 0.0001) compared to non-cfs controls. this study supports the further examination of the role of proinflammatory mediators in cfs. furthermore, the clinical testing of> blockers and other anti-inflammatory agents for the treatment of this disease is warranted.
A Look at Infectious Agents as a Possible Causative Factor in Cardiovascular Disease: Part III
The link between infection and cardiovascular disease has been assessed by measuring the presence of antibodies against the pathogen. There are several mechanisms by which the immune response to a virus can result in immunopathology. Knowledge about molecular mimicry...
